The European Cancer Organization supported its
statement by proposing a variety of mechanisms for the protective effect of cereal fibre.
The European Cancer Prevention Consensus Statement is, however, not
findings from some prospective studies where no protective effect of dietary fibre against
colorectal cancer was found (Fuchs et al. 1999, Pietinen et al. 1999, Lundin et al.
2001c, Terry et al. 2001a). However, a recent study of Larsson et al (2005) suggested that high
consumption of whole grains is associated with a lower risk of
colon cancer among women. Similar
results were found in a study of Bingham et
al. (2003) where doubling of total dietary fibre intake from foods in
with low average intake of dietary fibre could
reduce the risk of colorectal cancer by 40%.
results show the complexity of the relationship between diet and cancer, and are expected
to be followed up by large-scale prospective studies using questionnaires and biomarkers
in blood, including studies on populations with a high consumption of cereal fibre. More
dietary intervention studies with cancer or surrogate markers for cancer as endpoints are